B-Cell Malignant Non-Hodgkin’s Lymphoma of the Sphenoid Sinus Cavity: a Case Report and Brief Review of the Literature

Lymphoma is usually the malignant tumor which originates from lymph node or lymph-tissues. The nasal cavity and paranasal sinuses are rare primary sites for lymphoma. In the paranasal sinuses, lymphoma of maxillary sinuses is the most common, ethmoidal sinuses is more than that of frontal sinuses, sphenoid sinuses is the least. The most common presenting symptoms are nasal obstruction, rhinorrhoea and epistaxia. The majority of the malignant non-Hodgkin’s lymphoma of the sinonasal tract is T/NK cell lymphoma, while B cell lymphoma is rare. The B-cell malignant nonHodgkin’s lymphoma of the sphenoid sinus cavity has never been reported in the previous literature. In this report, we present a case of B-cell malignant non-Hodgkin’s lymphoma of the sphenoid sinus, and the important immunohistological marks including CD3, CD20, CD79a and CD45RO are all positive.